Woman's face 'burnt off' after reaction to depression drug lamotrigine

Woman's face 'burnt off' after reaction to depression drug lamotrigineThe woman spent 66 days in the hospital with time in intensive careNewsNeil Shaw Assistant Editor (Money and Lifestyle)07:23, 13 Apr 2026View 3 ImagesThe reaction started with red blisters across her faceThis article contains images some may find disturbing.‌A woman’s face started to burn off and blister severely after her depression medication triggered a reaction. The 42-year-old was rushed into hospital with red and blistered skin to her face, head, neck and torso.‌Doctors found that the patient had been prescribed the drug lamotrigine to help manage her depression, which they believe had triggered toxic epidermal necrolysis (TEN). TEN is a rare, life-threatening skin disorder, characterised by widespread blistering, necrosis, and detachment of the skin.‌While uncommon, doctors noted reactions to lamotrigine had been reported before. The patient’s symptoms had begun three weeks before, gradually worsening until she was taken into the ICU for urgent treatment, with her face most severely affected.View 3 ImagesDay 66, when she was released from hospital‌Upon her admission, she was started on a course of several antibiotics, as well as an antibacterial biomaterial being used for tissue regeneration on her facial wounds. Four days in, she showed signs of healing, and the treatment continued with evaluations every other day.She remained in hospital for 66 days, with doctors monitoring her progress as her skin slowly healed. Pictures showing the progress of her condition throughout her time in hospital, as well as during a follow-up appointment six months after she was discharged show the incredible recovery she was able to make, with her skin visibly less scarred.View 3 ImagesThe woman four days after having bandages removedArticle continues belowDoctors described the affected areas as having undergone “excellent” restoration at the follow-up appointment. The woman was treated at Hosp...