Milan make their competitive debut under Ruben Amorim, including Goncalo Ramos, Mario Gila and Ruben Loftus-Cheek for the trip to Torino, but Rafael Leao is out.
It kicks off at the Stadio Olimpico Grande Torino at 19.45 UK time (20.45 CEST).
The Rossoneri had a poor pre-season until the victory over Amorim’s old club Manchester United, and are still very much a work in progress.
Rafael Leao is injured anyway, so doesn’t make the trip even taking transfer speculation into account, with Christopher Nkunku, Santiago Gimenez, Fikayo Tomori and Youssouf Fofana all frozen out pending sales.
Mike Maignan starts after the World Cup, but Adrien Rabiot hasn’t played a minute of football since the tournament, so is only ready for the bench.
Surprisingly, Luka Modric is also initially rested.
Yunus Musah gets the nod in midfield along with Ardon Jashari, with Pervis Estupinan and Samuel Chukwueze on the wings.
Alphadjo Cissè impressed in pre-season and supports massive signing Goncalo Ramos with Ruben Loftus-Cheek, but Diego Moreira is ready for his debut off the bench.
Torino squeezed past Carrarese 1-0 in the Coppa Italia last week thanks to a Giovanni Simeone penalty, the first competitive match under new coach and former Milan player Ignazio Abate.
The pitch was in a dismal state during that game, so the Lega Serie A ordered them to make emergency repairs, but it remains rather patchy.
Duvan Zapata, Tino Anjorin, Pietro Pellegri and Franco Israel are injured, with new signing Eray Comert suspended.
Fresh arrivals Pietro Comuzzo and Kian Fitz-Jim go straight into the starting XI again, with Simeone preferred to Che Adams.
Torino vs. Milan line-ups
Torino: Mascardi; Coco, Ismajli, Comuzzo; Pedersen, Fitz-Jim, Gineitis, Cacciamani; Vlasic, Casadei; Simeone
Milan: Maignan; Gila, De Winter, Pavlovic; Chukwueze, Musah, Jashari, Estupinan; Loftus-Cheek, Cissè; Goncalo Ramos
